The Neurotrauma Research Program
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Investigators

Chief Investigator

  • Stuart Hodgetts

Associate Investigators

  • Prof Alan Harvey
  • Prof Gong Chen

Institutions

  • Perron Institute for Neurological and Translational Science
  • University of Western Australia
  • Penn State University
  • Jinan University

Project

Direct in vivo reprogramming of host astrocytes into functional neurons in the injured spinal cord

Year: 2019

Loss of neurons and networks after neurotrauma is considered irreversible, leading to significant functional impairment. Most therapies trialed for spinal cord injury (SCI) in humans have met with little or no success. The potential of generating new neurons to replace dead ones, and potentially initiate some form of circuit reconstruction, is a holy grail of restorative neurology, with obvious potential benefit to patients. In vivo reprogramming in the spinal cord is a new technology, but holds great promise. We are currently investigating this approach to treat spinal cord stroke. We will extend these studies to clinically relevant models of SCI.

Contact

Address
c/o Perron Institute 8 Verdun St, Nedlands, WA 6009
Email
nrp@perron.uwa.edu.au

Latest News

  • Symposium of Western Australian Neuroscience 2020 – registrations now openSeptember 15, 2020 - 6:55 am
  • NRP ICWA grant awarded for spinal cord repairMarch 2, 2020 - 2:19 am
  • Australasian Neuroscience Society (ANS) February 28, 2020 - 8:07 am
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